Mass Galla chinesis et camelliae Fermentata (Chinese gall leaven, CGL) was investigated for activities against Helicobacter pylori\n(H. pylori) both in vitro and in vivo.The agar dilution method and time-kill curves, as in vitro assays and an in vivo study using a\nKunming mice model, were performed. CGL demonstrated a strong anti-Helicobacter pylori activity in vitro with the minimal\ninhibitory concentrations (MICs) against multiple H. pylori strains of 0.5âË?¼8mg/ml and the decreasing trend time-kill curves\nwhen increasing CGL concentrations. H. pylori eradication rates in vivo were evaluated based on rapid urease test (RUT) and\nhistopathologic criteria. Results revealed that the eradication rates in the CGL groups were 40% (4/10) in the high dosage group,\n33% (4/11) in the medium dosage group, and 18% (2/11) in the low dosage group, with the difference between the high dosage and\nH. pylori control groups being significant (
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